Rheumatology is a multispecialty of medicine that focuses on the diagnosis, treatment, and evaluation of patients with a wide range of associated disorders that mostly affect the joints but also frequently present with extraarticular symptoms such as uveitis. They can also show up in disorders related to the skin, heart, kidneys, lungs, or gastrointestinal system. With pathogeneses that interact with numerous hereditary variables as well as a wide range of different environmental influences, the majority of rheumatic diseases are complex or multifactorial entities. Our understanding of rheumatic illnesses has advanced as a result of the advent of "omics" approaches. These advances include not only the identification of several susceptibility genes but also other environmental factors such as ultraviolet (UV) radiation, vitamin D levels, certain infections, or the patient microbiome.
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